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1.

N⁶-methyladenosine (m⁶A) is an endogenous A3 adenosine receptor ligand.

Ogawa, Akiko; Nagiri, Chisae; Shihoya, Wataru; Inoue, Asuka; Kawakami, Kouki; Hiratsuka, Suzune; Aoki, Junken; Ito, Yasuhiro; Suzuki, Takeo; Suzuki, Tsutomu; Inoue, Toshihiro; Nureki, Osamu; Tanihara, Hidenobu; Tomizawa, Kazuhito; Wei, Fan-Yan.

Mol Cell; 81(4): 659-674.e7, 2021 02 18.

Artículo en Inglés | MEDLINE | ID: mdl-33472058

2.

Pathological mutations promote proteolysis of mitochondrial tRNA-specific 2-thiouridylase 1 (MTU1) via mitochondrial caseinolytic peptidase (CLPP).

Ahmad, Raja Norazireen Raja; Zhang, Long-Teng; Morita, Rikuri; Tani, Haruna; Wu, Yong; Chujo, Takeshi; Ogawa, Akiko; Harada, Ryuhei; Shigeta, Yasuteru; Tomizawa, Kazuhito; Wei, Fan-Yan.

Nucleic Acids Res; 52(3): 1341-1358, 2024 Feb 09.

Artículo en Inglés | MEDLINE | ID: mdl-38113276

3.

Extracellular N⁶ -isopentenyladenosine (i⁶A) addition induces cotranscriptional i⁶A incorporation into ribosomal RNAs.

Yakita, Maya; Chujo, Takeshi; Wei, Fan-Yan; Hirayama, Mayumi; Kato, Koji; Takahashi, Nozomu; Naganuma, Kenta; Nagata, Masashi; Kawahara, Kenta; Nakayama, Hideki; Tomizawa, Kazuhito.

RNA; 28(7): 1013-1027, 2022 07.

Artículo en Inglés | MEDLINE | ID: mdl-35414588

4.

Aberrant RNA processing contributes to the pathogenesis of mitochondrial diseases in trans-mitochondrial mouse model carrying mitochondrial tRNALeu(UUR) with a pathogenic A2748G mutation.

Tani, Haruna; Ishikawa, Kaori; Tamashiro, Hiroaki; Ogasawara, Emi; Yasukawa, Takehiro; Matsuda, Shigeru; Shimizu, Akinori; Kang, Dongchon; Hayashi, Jun-Ichi; Wei, Fan-Yan; Nakada, Kazuto.

Nucleic Acids Res; 50(16): 9382-9396, 2022 09 09.

Artículo en Inglés | MEDLINE | ID: mdl-35998911

5.

Movements of Ancient Human Endogenous Retroviruses Detected in SOX2-Expressing Cells.

Monde, Kazuaki; Satou, Yorifumi; Goto, Mizuki; Uchiyama, Yoshikazu; Ito, Jumpei; Kaitsuka, Taku; Terasawa, Hiromi; Monde, Nami; Yamaga, Shinya; Matsusako, Tomoya; Wei, Fan-Yan; Inoue, Ituro; Tomizawa, Kazuhito; Ono, Akira; Era, Takumi; Sawa, Tomohiro; Maeda, Yosuke.

J Virol; 96(9): e0035622, 2022 05 11.

Artículo en Inglés | MEDLINE | ID: mdl-35420440

6.

Cooperative methylation of human tRNA3Lys at positions A58 and U54 drives the early and late steps of HIV-1 replication.

Fukuda, Hiroyuki; Chujo, Takeshi; Wei, Fan-Yan; Shi, Sheng-Lan; Hirayama, Mayumi; Kaitsuka, Taku; Yamamoto, Takahiro; Oshiumi, Hiroyuki; Tomizawa, Kazuhito.

Nucleic Acids Res; 49(20): 11855-11867, 2021 11 18.

Artículo en Inglés | MEDLINE | ID: mdl-34642752

7.

Export of RNA-derived modified nucleosides by equilibrative nucleoside transporters defines the magnitude of autophagy response and Zika virus replication.

Shi, Sheng-Lan; Fukuda, Hiroyuki; Chujo, Takeshi; Kouwaki, Takahisa; Oshiumi, Hiroyuki; Tomizawa, Kazuhito; Wei, Fan-Yan.

RNA Biol; 18(sup1): 478-495, 2021 10 15.

Artículo en Inglés | MEDLINE | ID: mdl-34382915

8.

Mammalian NSUN2 introduces 5-methylcytidines into mitochondrial tRNAs.

Shinoda, Saori; Kitagawa, Sho; Nakagawa, Shinichi; Wei, Fan-Yan; Tomizawa, Kazuhito; Araki, Kimi; Araki, Masatake; Suzuki, Takeo; Suzuki, Tsutomu.

Nucleic Acids Res; 47(16): 8734-8745, 2019 09 19.

Artículo en Inglés | MEDLINE | ID: mdl-31287866

9.

Metabolic and chemical regulation of tRNA modification associated with taurine deficiency and human disease.

Asano, Kana; Suzuki, Takeo; Saito, Ayaka; Wei, Fan-Yan; Ikeuchi, Yoshiho; Numata, Tomoyuki; Tanaka, Ryou; Yamane, Yoshihisa; Yamamoto, Takeshi; Goto, Takanobu; Kishita, Yoshihito; Murayama, Kei; Ohtake, Akira; Okazaki, Yasushi; Tomizawa, Kazuhito; Sakaguchi, Yuriko; Suzuki, Tsutomu.

Nucleic Acids Res; 46(4): 1565-1583, 2018 02 28.

Artículo en Inglés | MEDLINE | ID: mdl-29390138

10.

Mitochondrial localization of PABPN1 in oculopharyngeal muscular dystrophy.

Doki, Tsukasa; Yamashita, Satoshi; Wei, Fan-Yan; Hara, Kentaro; Yamamoto, Takahiro; Zhang, Ziwei; Zhang, Xiao; Tawara, Nozomu; Hino, Hirotake; Uyama, Eiichiro; Kurashige, Takashi; Maruyama, Hirofumi; Tomizawa, Kazuhito; Ando, Yukio.

Lab Invest; 99(11): 1728-1740, 2019 11.

Artículo en Inglés | MEDLINE | ID: mdl-30894671

11.

Noninvasive diagnosis of TRIT1-related mitochondrial disorder by measuring i⁶ A37 and ms² i⁶ A37 modifications in tRNAs from blood and urine samples.

Takenouchi, Toshiki; Wei, Fan-Yan; Suzuki, Hisato; Uehara, Tomoko; Takahashi, Takao; Okazaki, Yasushi; Kosaki, Kenjiro; Tomizawa, Kazuhito.

Am J Med Genet A; 179(8): 1609-1614, 2019 08.

Artículo en Inglés | MEDLINE | ID: mdl-31140736

12.

Tctex-1 controls ciliary resorption by regulating branched actin polymerization and endocytosis.

Saito, Masaki; Otsu, Wataru; Hsu, Kuo-Shun; Chuang, Jen-Zen; Yanagisawa, Teruyuki; Shieh, Vincent; Kaitsuka, Taku; Wei, Fan-Yan; Tomizawa, Kazuhito; Sung, Ching-Hwa.

EMBO Rep; 18(8): 1460-1472, 2017 08.

Artículo en Inglés | MEDLINE | ID: mdl-28607034

13.

Regulation of growth hormone biosynthesis by Cdk5 regulatory subunit associated protein 1-like 1 (CDKAL1) in pituitary adenomas.

Takesue, Yoshihiro; Wei, Fan-Yan; Fukuda, Hiroyuki; Tanoue, Yuki; Yamamoto, Takahiro; Chujo, Takeshi; Shinojima, Naoki; Yano, Shigetoshi; Morioka, Motohiro; Mukasa, Akitake; Kuratsu, Junichi; Tomizawa, Kazuhito.

Endocr J; 66(9): 807-816, 2019 Sep 28.

Artículo en Inglés | MEDLINE | ID: mdl-31189758

14.

Cdk5rap1-mediated 2-methylthio-N6-isopentenyladenosine modification is absent from nuclear-derived RNA species.

Fakruddin, Md; Wei, Fan Yan; Emura, Shohei; Matsuda, Shigeru; Yasukawa, Takehiro; Kang, Dongchon; Tomizawa, Kazuhito.

Nucleic Acids Res; 45(20): 11954-11961, 2017 Nov 16.

Artículo en Inglés | MEDLINE | ID: mdl-28981754

15.

Reactive sulfur species regulate tRNA methylthiolation and contribute to insulin secretion.

Takahashi, Nozomu; Wei, Fan-Yan; Watanabe, Sayaka; Hirayama, Mayumi; Ohuchi, Yuya; Fujimura, Atsushi; Kaitsuka, Taku; Ishii, Isao; Sawa, Tomohiro; Nakayama, Hideki; Akaike, Takaaki; Tomizawa, Kazuhito.

Nucleic Acids Res; 45(1): 435-445, 2017 Jan 09.

Artículo en Inglés | MEDLINE | ID: mdl-27568003

16.

Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury.

Wu, Yong; Wei, Fan-Yan; Kawarada, Layla; Suzuki, Takeo; Araki, Kimi; Komohara, Yoshihiro; Fujimura, Atsushi; Kaitsuka, Taku; Takeya, Motohiro; Oike, Yuichi; Suzuki, Tsutomu; Tomizawa, Kazuhito.

PLoS Genet; 12(9): e1006355, 2016 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-27689697

17.

Sirtuin 7 is involved in the consolidation of fear memory in mice.

Islam, Md Safiqul; Wei, Fan-Yan; Ohta, Kunimasa; Shigematsu, Naoki; Fukuda, Takaichi; Tomizawa, Kazuhito; Yoshizawa, Tatsuya; Yamagata, Kazuya.

Biochem Biophys Res Commun; 495(1): 261-266, 2018 01 01.

Artículo en Inglés | MEDLINE | ID: mdl-29101029

18.

Lack of tRNA-i6A modification causes mitochondrial-like metabolic deficiency in S. pombe by limiting activity of cytosolic tRNATyr, not mito-tRNA.

Lamichhane, Tek N; Arimbasseri, Aneeshkumar G; Rijal, Keshab; Iben, James R; Wei, Fan Yan; Tomizawa, Kazuhito; Maraia, Richard J.

RNA; 22(4): 583-96, 2016 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-26857223

19.

Evolving specificity of tRNA 3-methyl-cytidine-32 (m3C32) modification: a subset of tRNAsSer requires N6-isopentenylation of A37.

Arimbasseri, Aneeshkumar G; Iben, James; Wei, Fan-Yan; Rijal, Keshab; Tomizawa, Kazuhito; Hafner, Markus; Maraia, Richard J.

RNA; 22(9): 1400-10, 2016 09.

Artículo en Inglés | MEDLINE | ID: mdl-27354703

20.

tRNA modifications and islet function.

Wei, Fan-Yan; Tomizawa, Kazuhito.

Diabetes Obes Metab; 20 Suppl 2: 20-27, 2018 09.

Artículo en Inglés | MEDLINE | ID: mdl-30230180

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